The Academy is pleased to provide you with access to information about the latest clinical trials in pain management.

~October 2007

New Clinical Trials October 2007
Below are abstracts of recent pain and pain management studies selected from the National Library of Medicine. Click on the link below each entry for the complete abstract.

California

Arthritis
City: San Diego
Summary: A Study Evaluating the Long-Term Safety of ThermoProfen™ in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee.

City: Westlake Village
Summary: A Study Evaluating the Long-Term Safety of ThermoProfen™ in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee.

Arthritis
City: Upland
Summary: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy of CRx-102 in Subjects With Symptomatic Knee Osteoarthritis. CRx-102 is a synergistic combination drug candidate containing the cardiovascular drug dipyridamole and a very low dose of the glucocorticoid prednisolone. CRx-102 is believed to work through a novel mechanism of action in which dipyridamole selectively amplifies the anti-inflammatory and immunomodulatory activities of the glucocorticoid without replicating the dose-dependent adverse effects

Back Pain
City: Los Angeles
Summary: A study evaluating the safety and effectiveness of the coflex device compared to the control.

City: Escondido
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Connecticut

Back Pain
City: New Haven
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Florida

Analgesics, Opioid
City: Tampa
Summary: A research study evaluating an investigational treatment, injected daily, when compared to placebo (inactive substance), for constipation caused by the pain medicine (opioids) usually prescribed for men and women with chronic, non-cancer related pain.

Back Pain
City: Clearwater
Summary: A clinical research study of an investigational medication for a possible once-a-day treatment of your moderate to severe chronic low back pain.

City: Gainsville
Summary: study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Digestive System Diseases
City: Ocala
Summary: A clinical research study for men and women who suffer from Irritable Bowel Syndrome with constipation.

Fibromyalgia
City: Ocala
Summary: A study of an investigational medication for the treatment of Fibromyalgia.

Headache Disorders
City: Maitland
Summary: A research study with an investigational medication for the prevention of migraine headaches.

Nervous System Diseases
City: Clearwater
Summary: A clinical research study of an investigational oral medication in people with hand, foot, or leg pain caused by diabetes-related nerve damage.

City: Tampa
Summary: A research study to evaluate an investigational pain medication that is unique to how it effects pain due to chronic diabetic neuropathy.

Georgia

Fibromyalgia
City: Atlanta
Summary: A research study testing an investigational drug for people with Fibromyalgia.

Headache Disorders
City: Atlanta
Summary: A research study that may help develop a new medication for migraine prevention.

Illinois

Back Pain
City: Lombard
Summary: A study investigating the efficacy of different amounts of total treatment dosage over six weeks in 60 volunteer subjects with lumbar spinal stenosis.

Nervous System Diseases
City: Chicago
Summary: A study evaluating the effect of epoetin alfa on HIV-associated neuropathy by measuring changes in nerve fiber density and pain ratings.

Indiana

Back Pain
City: Fort Wayne
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Kentucky

Fibromyalgia
City: Lexington
Summary: A study investigating the effectiveness of a study drug in females with fibromyalgia syndrome.

Maryland

Nervous System Diseases
City: Baltimore
Summary: A study evaluating the effect of epoetin alfa on HIV-associated neuropathy by measuring changes in nerve fiber density and pain ratings.

Massachusetts

Arthritis
City: Boston
Summary: A study measuring the effect of collagen hydrolysate on knee cartilage as measrued by MRI.

Michigan

Endometriosis
City: Pawpaw
Summary: A clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Missouri

Nervous System Diseases
City: St. Louis
Summary: A study evaluating the effect of epoetin alfa on HIV-associated neuropathy by measuring changes in nerve fiber density and pain ratings.

New Mexico

Nervous System Diseases
City: Albuquerque
Summary: A clinical research study of an investigational medication for diabetic neuropathy pain.

New York

Back Pain
City: New York
Summary: A study evaluating the safety and effectiveness of the coflex device compared to the control.

City: Syracuse
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Headache Disorders
City: Lake Success
Summary: People with acute migraine headaches are asked to participate in a research study being conducted by North Shore – LIJ Medical Center.

Nervous System Diseases
City: New York
Summary: A study evaluating the effect of epoetin alfa on HIV-associated neuropathy by measuring changes in nerve fiber density and pain ratings.

North Carolina

Arthritis
City: Chapel Hill
Summary: A study to determine the whether the Walk with Ease (WWE) program in its 2 version (group-assisted and self-directed) can increase physical activity and fitness levels among individuals (18 years and older) with arthritis over the long-term.

Back Pain
City: Durham
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

North Dakota

Endometriosis
City: Jamestown
Summary: A clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Oklahoma

Back Pain
City: Oklahoma City
Summary: A study seeking individuals with moderate to severe low back pain for possible participation in the study of an investigational medication.

Nervous System Diseases
City: Oklahoma City
Summary: A clinical research study seeks individuals who suffer from painful diabetic peripheral neuropathy.

Pennsylvania

Nervous System Diseases
City: Philadelphia
Summary: A study evaluating the effect of epoetin alfa on HIV-associated neuropathy by measuring changes in nerve fiber density and pain ratings

Tennessee

Back Pain
City: Bristol
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Back Pain
City: Nashville
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Texas

Abdominal Pain
City: Houston
Summary: Study to determine if fiber versus a probiotic versus placebo improves symptoms in children with recurrent abdominal pain/irritable bowel syndrome. This study will also determine possible ways fiber, a probiotic, or placebo improve(s) symptoms in children with recurrent abdominal pain/irritable bowel syndrome by carrying out gastrointestinal function tests and psychological questionnaires.

Arthritis
City: Houston
Summary: A Study Evaluating the Long-Term Safety of ThermoProfen™ in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee.

Back Pain
City: Plano
Summary: A study assessing whether the Stabilimax NZ™ is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal stenosis at one or two contiguous vertebral levels from L1-S1.

Endometriosis
City: Dallas
Summary: A clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Endometriosis
City: Fort Worth
Summary: A clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Endometriosis
City: San Antonio
Summary: A clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

West Virginia

Arthritis
City: Morgantown
Summary: A study to determine if an evidence-based, community-delivered physical activity program, EnhanceFitness, yields benefits for participants with arthritis.


American Academy of Pain Management is the nation's largest interdisciplinary organization serving clinicians who treat people with pain through education, setting standards of care, and advocacy.
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www.aapainmanage.org