The Academy is pleased to provide you with access to information about the latest clinical trials in pain management.

~August 2008

New Clinical Trials August 2008
Below are abstracts of recent pain and pain management studies selected from the National Library of Medicine. Click on the link below each entry for the complete abstract.

Arizona

Arthritis
City: Scottsdale
Summary: A clinical research study of an investigational medication for the aches and pains of rheumatoid arthritis.

Fibromyalgia
City: Phoenix
Summary: A clinical research study evaluating the effectiveness of an investigational drug for the symptoms associated with fibromyalgia.

Herpes Zoster
City: Scottsdale
Summary: A clinical research study of an investigational vaccine to see if it prevents shingles.

California

Arthritis
City: Spring Valley
Summary: A study of the safety and efficacy of epicutaneously applied Diractin® (ketoprofen in Transfersome® Gel) for the treatment of osteoarthritis of the knee

Cancer Pain
City: Los Angeles
Summary: A trial evaluating the effectiveness and safety of ExAblate (MR guided Focused Ultrasound, MRgFUS) for the palliation of pain from metastatic bone tumors in patients who are not suitable candidates to receive additional radiation therapy.

Nervous System Diseases
City: Carmichael
Summary: A study comparing the efficacy and safety of ARC-4558 (clonidine topical gel 0.1%) with placebo in the management of pain associated with painful diabetic neuropathy.

Connecticut

Fibromyalgia
City: Danbury
Summary: A clinical research study of a drug for fibromyalgia in comparison to an inactive placebo.

Substance Related Disorders
City: New Haven
Summary: A study involving the development of an integrated psychotherapy that addresses both chronic pain and opioid dependence(POD).

Florida

Arthritis
City: New Port Richey
Summary: A study of the safety and efficacy of epicutaneously applied Diractin® (ketoprofen in Transfersome® Gel) for the treatment of osteoarthritis of the knee

Fibromyalgia
City: Deland
Summary: A research study seeks individuals suffering from fibromyalgia symptoms.

Headache Disorders
City: Palm Beach Gardens
Summary: A research study evaluating the safety and effectiveness of an investigational drug for the treatmant of migraines.

Nervous System Diseases
City: Palm Beach Gardens
Summary: A research study seeks individuals who suffer with pain caused by post herpetic neuralgia.

Georgia

Arthritis
City: Marietta
Summary: A study of the safety and efficacy of epicutaneously applied Diractin® (ketoprofen in Transfersome® Gel) for the treatment of osteoarthritis of the knee

City: Stockbridge
Summary: A study of the safety and efficacy of epicutaneously applied Diractin® (ketoprofen in Transfersome® Gel) for the treatment of osteoarthritis of the knee

Digestive System Diseases
City: Stockbridge
Summary: A clinical research study for bowel dysfunction caused by pain medications such as Vicodin®, Percocet®, and OxyContin®.

Nervous System Diseases
City: Atlanta
Summary: A clinical research study of an investigational vaccine to see if it prevents shingles.

City: Atlanta
Summary: A study of Metanx® in subjects with type 2 diabetic peripheral neuropathy.

Illinois

Digestive System Diseases
City: Bloomington
Summary: A clinical research study of an investigation drug vs. placebo (an inactive substance) for people who are currently receiving opioid therapy and are experiencing constipation due to pain medication use.

Kentucky

Headache Disorders
City: Lexington
Summary: A research study to determine if patent foramen ovale (PFO) closure using the AMPLATZER device can prevent migraine headaches compared to standard medical therapy.

Louisiana

Arthritis
City: New Orleans
Summary: A study of the safety and efficacy of epicutaneously applied Diractin® (ketoprofen in Transfersome® Gel) for the treatment of osteoarthritis of the knee

Nervous System Diseases
City: New Orleans
Summary: A study comparing the efficacy and safety of ARC-4558 (clonidine topical gel 0.1%) with placebo in the management of pain associated with painful diabetic neuropathy.

City: New Orleans
Summary: A study of Metanx® in subjects with type 2 diabetic peripheral neuropathy.

Massachusetts

Digestive System Diseases
City: Boston
Summary: A clinical research study investigating a medication for constipation caused by opioid medications such as percocet or morphine.

City: Boston
Summary: A study of subcutaneous MOA-728 for the treatment of opioid-induced constipation in subjects with chronic non-malignant pain.

City: Chestnut Hill
Summary: A study of the efficacy and safety of lubiprostone in patients with opioid-induced bowel dysfunction.

Headache Disorders
City: Brookline
Summary: A study investigating the effects of expectation and knowledge on rizatriptan and placebo treatment of acute migraine headache.

Nervous System Diseases
City: Worcester
Summary: A study comparing the efficacy and safety of ARC-4558 (clonidine topical gel 0.1%) with placebo in the management of pain associated with painful diabetic neuropathy.

Montana

Headache Disorders
City: Missoula
Summary: A study of an investigational inhaled migraine therapy for individuals with migraines of moderate to severe in intensity.

Nebraska

Nervous System Diseases
City: Omaha
Summary: A study of Metanx® in subjects with type 2 diabetic peripheral neuropathy.

New Jersey

Back Pain
City: Kenilworth
Summary: A study to determine which of two strategies, when used by referring physicians is superior in the diagnosis of axial spondyloarthritis (AS) by rheumatologists.

New York

Arthritis
City: New York
Summary: A study of the safety and efficacy of epicutaneously applied Diractin® (ketoprofen in Transfersome® Gel) for the treatment of osteoarthritis of the knee

Cancer Pain
City: New York
Summary: A trial evaluating the effectiveness and safety of ExAblate (MR guided Focused Ultrasound, MRgFUS) for the palliation of pain from metastatic bone tumors in patients who are not suitable candidates to receive additional radiation therapy.

Headache Disorders
City: New Hyde Park
Summary: A research study on the quality of life in patients with migraines.

Nervous System Diseases
City: New York
Summary: A study of Metanx® in subjects with type 2 diabetic peripheral neuropathy.

North Carolina

Nervous System Diseases
City: Winston-Salem
Summary: A study comparing the efficacy and safety of ARC-4558 (clonidine topical gel 0.1%) with placebo in the management of pain associated with painful diabetic neuropathy.

Pennsylvania

Headache Disorders
City: Johnstown
Summary: A study testing a standardized set of acupuncture points on migraine patients to reduce frequency and intensity of headaches.

South Carolina

Arthritis
City: Goose Creek
Summary: A study of the safety and efficacy of epicutaneously applied Diractin® (ketoprofen in Transfersome® Gel) for the treatment of osteoarthritis of the knee

Nervous System Diseases
City: Murrells Inlet
Summary: A study comparing the efficacy and safety of ARC-4558 (clonidine topical gel 0.1%) with placebo in the management of pain associated with painful diabetic neuropathy.

Tennessee

Herpes Zoster
City: Nashville
Summary: A research study to evaluate the investigational use of ZOSTAVAX™ versus placebo (an inactive substance) in adults aged fifty to fifty-nine.

Texas

Cancer Pain
City: Houston, TX
Summary: A clinical trial investigating how well methadone works compared with morphine or oxycodone in treating pain in patients with cancer.

Headache Disorders
City: San Antonio
Summary: A clinical research study of an investigational inhaled medication for migraine headaches.

Nervous System Diseases
City: Dallas
Summary: A study of Metanx® in subjects with type 2 diabetic peripheral neuropathy.

City: San Antonio
Summary: A research study of an investigational medication in individuals who have experienced pain for at least 3 months after shingles (herpes zoster) have healed.

City: San Antonio
Summary: study comparing the efficacy and safety of ARC-4558 (clonidine topical gel 0.1%) with placebo in the management of pain associated with painful diabetic neuropathy.

City: Temple
Summary: A study of Metanx® in subjects with type 2 diabetic peripheral neuropathy.

Utah

Fibromyalgia
City: Salt Lake City
Summary: A research study seeks individuals experiencing the pain and exhaustion of fibromyalgia.


American Academy of Pain Management is the nation's largest interdisciplinary organization serving clinicians who treat people with pain through education, setting standards of care, and advocacy.
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