The Academy is pleased to provide you with access to information about the latest clinical trials in pain management.

~July 2008

New Clinical Trials July 2008
Below are abstracts of recent pain and pain management studies selected from the National Library of Medicine. Click on the link below each entry for the complete abstract.

California

Abdominal Pain
City: San Diego
Summary: A study investigating the efficacy of S-adenosyl methionine (SAM-e) for recurrent abdominal pain in children.

Digestive System Diseases
City: Laguna Hills
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

City: Long Beach
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

City: San Diego
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

Connecticut

Nervous System Diseases
City: Waterbury
Summary: A trial of [S,S]-reboxetine in patients with chronic painful diabetic peripheral neuropathy.

Florida

Digestive System Diseases
City: Chiefland
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

City: Plantation
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

City: West Palm Beach
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

City: Weston
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

Headache Disorders
City: DeLand
Summary: A research study seeks individuals diagnosed with migraines that occur at least once a month for at least 3 months.

Nervous System Diseases
City: DeLand
Summary: A research study seeks individuals who suffer from painful neuropathy due to type I or type II diabetes.

Georgia

Digestive System Diseases
City: Atlanta
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

Illinois

Digestive System Diseases
City: Bloomington
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

Maryland

Back Pain
City: Bethesda
Summary: A study to assess the safety of the Biostat Disc Augmentation System for the treatment of chronic low-back (lumbar) pain due to symptomatic internal disc disruptions (IDD) and to obtain preliminary efficacy information.

Substance Related Disorders
City: Baltimore
Summary: A study assessing the abuse liability of Acurox (oxycodone HCl and niacin) tablets in subjects with a history of opioid abuse.

Massachusetts

Cancer Pain
City: Burlington
Summary: A study evaluating the effectiveness and safety of ExAblate treatment of metastatic bone tumors for the palliation of pain in patients who are not candidates for radiation therapy

Michigan

Pelvic Pain
City: Royal Oak
Summary: A study evaluating the efficacy of CC-10004 in patients with chronic prostatitis or chronic pelvic pain syndrome (CP/CPPS).

Minnesota

Digestive System Diseases
City: Edina
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation

Headache Disorders
City: Minneapolis
Summary: A research study evaluating the effects of an investigational drug on individuals who experience 2 to 8 migraine headaches per month.

Missouri

Digestive System Diseases
City: St Peters
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation

Montana

Nervous System Diseases
City: Missoula
Summary: A research study seeks individuals who suffer from post-herpetic neuralgia.

New Mexico

Digestive System Diseases
City: Albuquerque
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

New York

Cancer Pain
City: New York
Summary: A study evaluating the effectiveness and safety of ExAblate treatment of metastatic bone tumors for the palliation of pain in patients who are not candidates for radiation therapy

Digestive System Diseases
City: Great Neck
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

Nervous System Diseases
City: Rochester
Summary: A research study of an investigational drug for those who have diabetes and a condition called diabetic neuropathy, which is nerve damage caused by diabetes.

Ohio

Digestive System Diseases
City: Canton
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

City: Dayton
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

Endometriosis
City: Cleveland
Summary: A research study evaluating whether an investigational drug decreases the symptoms associated with endometriosis, such as pain.

Fibromyalgia
City: Cincinnati
Summary: A clinical research study to evaluate the safety and effect of an investigational medication for people with fibromyalgia.

Headache Disorders
City: Cincinnati
Summary: A clinical research study of an investigational drug for the treatment of migraines.

City: Cincinnati
Summary: A clinical study of an investigational medication for migraines.

City: Cleveland
Summary: A research study seeks individuals who are on butalbital containing prescription treatment for your migraine headaches at least once a month.

Herpes Zoster
City: Cincinnati
Summary: A clinical research study evaluating the safety and effectiveness of an investigational use of an approved vaccine for shingles.

Nervous System Diseases
City: Cincinnati
Summary: A clinical research study of an investigational medication for people with diabetic leg pain or diabetic neuropathy.

City: Cleveland
Summary: A research study evaluating the safety and effectiveness of an investigational drug for the treatment of pain due to post-herpetic neuralgia.

Pennsylvania

Fibromyalgia
City: Portland
Summary: A clinical trial assessing the efficacy and safety of two different transdermal doses of rotigotine in subjects with signs and symptoms associated with fibromyalgia syndrome.

City: Souderton
Summary: A clinical trial assessing the efficacy and safety of two different transdermal doses of rotigotine in subjects with signs and symptoms associated with fibromyalgia syndrome.

South Carolina

Headache Disorders
City: Mt. Pleasant
Summary: A research study evaluating the effects of an investigational medication on individuals who suffer from migraines.

Tennessee

Digestive System Diseases
City: Chattanooga
Summary: A Phase 2 study designed to evaluate the safety and efficacy of NKTR-118 (PEG-naloxol) in patients with opioid-induced constipation.

Nervous System Diseases
City: Nashville
Summary: A clinical research study seeks individuals suffering from post shingles pain at least 6 months after their rash has healed.

Texas

Analgesics, Non-Narcotic
City: Austin
Summary: A study evaluating the bioavailability of naproxen 375 mg in two formulations.

Back Pain
City: Tyler
Summary: study to assess the safety of the Biostat Disc Augmentation System for the treatment of chronic low-back (lumbar) pain due to symptomatic internal disc disruptions (IDD) and to obtain preliminary efficacy information.

Fibromyalgia
City: Bryan
Summary: A study providing medical assessments, diagnostic tests, and investigational medication to participants with fibromyalgia.

Headache Disorders
City: Temple
Summary: A study examining the combined effects of a continuous oral contraceptive (OC) regimen with supplemental frovatriptan therapy on headache severity and occurrence in subjects with documented menstrually associated migraines (MAM).

Nervous System Diseases
City: Bryan
Summary: A clinical research study seeks individuals who have had pain for at least three months after their shingles healed.

City: Dallas
Summary: research study to examine the effects of nerve decompression on decreasing the pain associated with diabetic neuropathy and increasing the sensation at the bottom of the foot.

Washington

Back Pain
City: Bellingham
Summary: A study to assess the safety of the Biostat Disc Augmentation System for the treatment of chronic low-back (lumbar) pain due to symptomatic internal disc disruptions (IDD) and to obtain preliminary efficacy information.


American Academy of Pain Management is the nation's largest interdisciplinary organization serving clinicians who treat people with pain through education, setting standards of care, and advocacy.
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www.aapainmanage.org