Arthritis (Knee)
City: San Diego
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Arthritis (Knee)
City: Carmichael, Fair Oaks
Purpose: A 2 Week, Randomized, Double Blind, Placebo And Positive Controlled, Parallel Group, Multicentre Study To Assess The Efficacy And Tolerability Of PF-00592379 In Patients With Moderate To Severe Pain Due To Osteoarthritis

Back Pain
City: Beverly Hills, Encinitas
Purpose: The purpose of this study is to demonstrate that the Wallis System (interspinous process implant) is equivalent to total disc replacement (TDR) for the treatment of mild to moderate degenerative disc disease (DDD) of the lumbar spine at the L4-L5 level.

Endometriosis
City: Los Angeles
Purpose: To evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Headache Disorders
City: Chico, Fair Oaks, Fresno, Fullerton, Huntington, Irvine, Newport Beach, Northridge, Redondo Beach, Roseville, Sacramento, San Diego, San Francisco, Santa Monica, Walnut Creek
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (postherpetic neuralgia)
City: Carmichael, Loma Linda, Los Angeles, Santa Monica
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

Colorado

Back Pain
City: Boulder
Purpose: The purpose of this study is to demonstrate that the Wallis System (interspinous process implant) is equivalent to total disc replacement (TDR) for the treatment of mild to moderate degenerative disc disease (DDD) of the lumbar spine at the L4-L5 level.

Headache Disorders
City: Colorado Springs, Denver
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Connecticut

Headache Disorders
City: Ridgefield, Fairfield
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (postherpetic neuralgia)
City: Fairfield
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

District Of Columbia

Back Pain
City: District Of Columbia
Purpose: The purpose of this study is to determine the optimal number of blocks before radiofrequency denervation. Three groups of patients will be studied. In group I, patients will undergo RF denervation based on history and physical exam alone. In group II, patients will undergo RF denervation based on a positive response to a single diagnostic block with local anesthetic. In group III, patients will undergo RF treatment only after a positive screening block and a positive confirmatory block.

Headache Disorders
City: District of Columbia
Purpose: The purpose of this study is to determine whether naratriptan, a medication approved for treatment of migraine, is effective in the treatment of post traumatic headache associated with cognitive dysfunction.

Florida

Analgesics, Non-Narcotic
City: Miami, Plantation, Tamarac
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Arthritis (Knee)
City: DeLand
Purpose: A 2 Week, Randomized, Double Blind, Placebo And Positive Controlled, Parallel Group, Multicentre Study To Assess The Efficacy And Tolerability Of PF-00592379 In Patients With Moderate To Severe Pain Due To Osteoarthritis Illinois

Back Pain
City: West Palm Beach
Purpose: The objective of this study is to determine the analgesic efficacy and safety of Buprenorphine Transdermal System (BTDS) 10 and 20 compared to placebo in opioid-naïve subjects with moderate to severe chronic low back pain.

Headache Disorders
City: Loxahatchee, Naples, Pensacola, St. Petersburg, West Palm Beach
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Georgia

Analgesics, Non-Narcotic
City: Atlanta
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Back Pain
City: Atlanta
Purpose: The objective of this study is to determine the analgesic efficacy and safety of Buprenorphine Transdermal System (BTDS) 10 and 20 compared to placebo in opioid-naïve subjects with moderate to severe chronic low back pain.

Headache Disorders
City: Atlanta, Savannah
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Idaho

Headache Disorders
City: Boise
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Illinois

Arthritis (Knee)
City: Springfield
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Back Pain
City: Morton Grove
Purpose: The purpose of this study is to demonstrate that the Wallis System (interspinous process implant) is equivalent to total disc replacement (TDR) for the treatment of mild to moderate degenerative disc disease (DDD) of the lumbar spine at the L4-L5 level.

Indiana

Analgesics, Non-Narcotic
City: Valparaiso
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Arthritis (Knee)
City: Evansville
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Headache Disorders
City: Anderson
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (painful diabetic neuropathy)
City: Evansville
Purpose: The purpose of this study is to evaluate Spinal Cord Stimulation (SCS) therapy in individuals who suffer from painful diabetic peripheral neuropathy

Iowa

Analgesics, Non-Narcotic
City: West Des Moines
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Back-Related Leg Pain
City: Davenport
Purpose: The primary aims of the project are to determine the clinical efficacy of chiropractic SMT plus self-care education versus self-care education alone in 192 patients with sub-acute and chronic BRLP in both the short-term (after 12 weeks) and long-term (after 52 weeks). The primary outcome variable is leg pain and secondary outcome variables include low back pain, disability, bothersomeness and frequency of symptoms, general health status, and fear avoidance behavior.

Nervous System Diseases (postherpetic neuralgia)
City: Des Moines
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

Kansas

Analgesics, Non-Narcotic
City: Prairie Village
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Headache Disorders
City: Overland Park
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Kentucky

Headache Disorders
City: Bardstown, Murray
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Louisiana

Analgesics, Non-Narcotic
City: Baton Rouge, Mandeville, Metarie, New Orleans
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Maryland

Analgesics, Non-Narcotic
City: Columbia, Baltimore, Owings Mills, Rockville
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Arthritis (Knee)
City: Baltimore
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Back Pain
City: Baltimore
Purpose: The purpose of this study is to determine the optimal number of blocks before radiofrequency denervation. Three groups of patients will be studied. In group I, patients will undergo RF denervation based on history and physical exam alone. In group II, patients will undergo RF denervation based on a positive response to a single diagnostic block with local anesthetic. In group III, patients will undergo RF treatment only after a positive screening block and a positive confirmatory block.

Massachusetts

Analgesics, Opioid
City: Boston
Purpose: to see if Ultram ER, an FDA-approved pain medication, would be helpful in providing pain relief in subjects whose chronic pain is not well controlled on narcotic pain medicine.

Analgesics, Opioid
City: Boston
Purpose: The study is looking at the effect of opioid (narcotic) pain medicines on pain sensation, threshold and tolerance

Cancer Pain
City: Boston
Purpose: To assess the safety and efficacy of PMI-150 (Intranasal Ketamine) as an analgesic for the treatment of breakthrough pain in cancer patients.

Headache Disorders
City: Wellesley Hills
Purpose: The objective of this trial is to assess the efficacy and safety of Staccato Loxapine in patients with migraine headache with or without aura in a clinical setting.

Nervous System Diseases (postherpetic neuralgia)
City: Boston
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

Michigan

Headache Disorders
City: Ann Arbor, Kalamazoo, Paw Paw, Protage
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Minnesota

Back-Related Leg Pain
City: Bloomington
Purpose: The primary aims of the project are to determine the clinical efficacy of chiropractic SMT plus self-care education versus self-care education alone in 192 patients with sub-acute and chronic BRLP in both the short-term (after 12 weeks) and long-term (after 52 weeks). The primary outcome variable is leg pain and secondary outcome variables include low back pain, disability, bothersomeness and frequency of symptoms, general health status, and fear avoidance behavior.

Headache Disorders
City: Minneapolis
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Missouri

Analgesics, Non-Narcotic
City: St. Louis
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Arthritis (Knee)
City: Kansas City
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Back Pain
City: Springfield
Purpose: The purpose of this study is to demonstrate that the Wallis System (interspinous process implant) is equivalent to total disc replacement (TDR) for the treatment of mild to moderate degenerative disc disease (DDD) of the lumbar spine at the L4-L5 level.

Headache Disorders
City: Springfield
Purpose: The purpose of this study is to determine whether naratriptan, a medication approved for treatment of migraine, is effective in the treatment of post traumatic headache associated with cognitive dysfunction.

Headache Disorders
City: St. Louis
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (postherpetic neuralgia)
City: St. Louis
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

Nebraska

Analgesics, Non-Narcotic
City: Omaha
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Headache Disorders
City: Omaha
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nevada

Headache Disorders
City: Las Vegas
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (postherpetic neuralgia)
City: Las Vegas
Purpose: TW

New Hampshire

Headache Disorders
City: Lebanon
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

New Jersey

Abdominal Pain
City: Morristown
Purpose: The purpose of this study is to evaluate the efficacy of a social learning and cognitive behavior therapy approach for treating children with Recurrent Abdominal Pain (RAP).

Analgesics, Non-Narcotic
City: Cherry Hill, Haddon Heights
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Analgesics, Non-Narcotic
City: Cedar Knolls
Purpose: A clinical research study evaluating an investigational medication that combines a medication with proven pain relief (NSAID) with proven stomach protection-into one singe pill.

Headache Disorders
City: Morristown, New Brunswick, Voorhees
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

New Mexico

Headache Disorders
City: Albuquerque
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

New York

Analgesics, Non-Narcotic
City: Mamaroneck, New York
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Arthritis (Knee)
City: New York
Purpose: A 2 Week, Randomized, Double Blind, Placebo And Positive Controlled, Parallel Group, Multicentre Study To Assess The Efficacy And Tolerability Of PF-00592379 In Patients With Moderate To Severe Pain Due To Osteoarthritis

Headache Disorders
City: Albany, Amherst, Endwell, New York, Plainview, Ridgewood, Rochester, Williamsville
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (chronic neuropathic pain after spinal cord injury)
City: New York
Purpose: To study the effectiveness of controlled-release morphine for chronic neuropathic pain after spinal cord injury

Nervous System Diseases (postherpetic neuralgia)
City: New York
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

North Carolina

Arthritis (Knee)
City: Raleigh
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Back Pain
City: Durham
Purpose: The purpose of this study is to demonstrate that the Wallis System (interspinous process implant) is equivalent to total disc replacement (TDR) for the treatment of mild to moderate degenerative disc disease (DDD) of the lumbar spine at the L4-L5 level.

Headache Disorders
City: Raleigh
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (postherpetic neuralgia)
City: Winston-Salem
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

Ohio

Back Pain
City: Toledo
Purpose: The objective of this study is to determine the analgesic efficacy and safety of Buprenorphine Transdermal System (BTDS) 10 and 20 compared to placebo in opioid-naïve subjects with moderate to severe chronic low back pain.

Fibromyalgia
City: Toledo
Purpose: Study of an investigational medication for Fibromyalgia

Headache Disorders
City: Cincinnati, Cleveland, Columbus, Westerville
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Oklahoma

Headache Disorders
City: Oklahama City
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Oregon

Headache Disorders
City: Eugene, Medford, Portland
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Pennsylvania

Analgesics, Non-Narcotic
City: Allentown, Morrisville, Philadelphia, Upland
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Arthritis (Knee)
City: Duncansville
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Back Pain
City: Pittsburgh
Purpose: The primary objective of this study is to determine the impact of an 8-week mindfulness-based stress reduction program on physical function and pain severity in community dwelling older adults with chronic low back pain.

Nervous System Diseases (postherpetic neuralgia)
City: Altoona, Philadelphia
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

Rhode Island

Arthritis (Knee)
City: Cumberland
Purpose: A 2 Week, Randomized, Double Blind, Placebo And Positive Controlled, Parallel Group, Multicentre Study To Assess The Efficacy And Tolerability Of PF-00592379 In Patients With Moderate To Severe Pain Due To Osteoarthritis

South Carolina

Analgesics, Non-Narcotic
City: Prosperity
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Headache Disorders
City: Greer
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Tennessee

Headache Disorders
City: Nashville
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Texas

Arthritis (Knee)
City: Houston, San Antonio
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Back Pain
City: Plano
Purpose: The purpose of this study is to demonstrate that the Wallis System (interspinous process implant) is equivalent to total disc replacement (TDR) for the treatment of mild to moderate degenerative disc disease (DDD) of the lumbar spine at the L4-L5 level.

Cancer Pain
City: Houston
Purpose: To evaluate the feasibility of providing acupuncture services to patients from the Pain Management Center (PMC) at M. D. Anderson Cancer Center (MDACC).

Headache Disorders
City: Dallas, Georgetown, Nassau Bay, Plano, San Antonio
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Nervous System Diseases (postherpetic neuralgia)
City: Amarillo, Dallas, Houston, San Antonio
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

Utah

Arthritis (Knee)
City: Salt Lake City
Purpose: This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults. ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.

Headache Disorders
City: Salt Lake City
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Vermont

Back Pain
City: Burlington
Purpose: The goal of this proposal is to test the overall hypothesis that subjects with chronic or recurrent low back pain have an abnormal soft tissue response to acupuncture needling, and that this altered response is associated with abnormal perimuscular connective tissue structure and biomechanics.

Virginia

Analgesics, Non-Narcotic
City: Virginia Beach, Roanoke
Purpose: The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a period of 1 year. The study will also assess dosage requirements over the long term; characterize adverse events and tolerability, sleep quality, and potential symptoms of withdrawal; characterize pain intensity scores and overall impression of change; and characterize patient-related health outcomes.

Headache Disorders
City: Charolottesville, Norfolk
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Washington

Abdominal Pain
City: Seattle
Purpose: The purpose of this study is to evaluate the efficacy of a social learning and cognitive behavior therapy approach for treating children with Recurrent Abdominal Pain (RAP).

Headache Disorders
City: Bremerton, Wenatchee
Purpose: This study was designed to determine long-term safety of Trexima compared to placebo for the treatment of acute migraine.

Temporomandibular Joint Disorders
City: Seattle
Purpose: This purpose of this study is to evaluate the safety and efficacy of treatment with nasal CO2 in the treatment of pain and other symptoms related to temporomandibular disorder

Wisconsin

Nervous System Diseases (postherpetic neuralgia)
City: Madison
Purpose: The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.

American Academy of Pain Management is the nation's largest interdisciplinary organization serving clinicians who treat people with pain through education, setting standards of care, and advocacy.
American Academy of Pain Management
13947 Mono Way #A • Sonora, CA 95370
www.aapainmanage.org