The Academy is pleased to provide you with access to information about the latest clinical trials in pain management.

~May 2007

New Clinical Trials May 2007
Below are abstracts of recent pain and pain management studies selected from the National Library of Medicine. Click on the link below each entry for the complete abstract.

ARIZONA

Fibromyalgia
City: Mesa, Peoria
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

Nervous System Diseases
City: Phoenix
Purpose: study of an investigational treatment for painful diabetic neuropathy

CALIFORNIA

Arthritis
City: Palo Alto
Purpose: develop brief versions of the classic 6-week Arthritis Self-Management Program and evaluate their effectiveness.

City: Long Beach
Purpose: This study is designed to assess the effects of socks and bedding materials on foot pain and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy or other conditions, e.g., peripheral arterial disease, regenerative joint disease)

Endometriosis
City: Burbank
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Fasciitis, Plantar
City: Long Beach
Purpose: This study is designed to assess the effects of socks and bedding materials on foot pain and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy or other conditions, e.g., peripheral arterial disease, regenerative joint disease)

Nervous System Diseases
City: Garden Grove
Purpose: This study is evaluating the effectiveness of 3 different dose levels of an investigational drug compared to placebo for patients who have been diagnosed with Type 1 or 2 Diabetes, experiencing painful neuropathy for 6 months to 10 years

City: Long Beach
Purpose: This study is designed to assess the effects of socks and bedding materials on foot pain and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy or other conditions, e.g., peripheral arterial disease, regenerative joint disease)

Peripheral Vascular Diseases
City: Long Beach
Purpose: This study is designed to assess the effects of socks and bedding materials on foot pain and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy or other conditions, e.g., peripheral arterial disease, regenerative joint disease)

FLORIDA

Arthritis
City: Clearwater
Purpose: We are conducting a research of 3 approved medications commonly used to treat pain due to osteoarthritis or Rheumatoid arthritis in people who also have or are at high risk for heart disease

Fibromyalgia
City: Deland, Delray Beach, Gainsville, Tampa, Sunrise
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

Nervous System Diseases
City: (Fort Myers), (Pembroke Pines)
Purpose: This study is evaluating the effectiveness of 3 different dose levels of an investigational drug compared to placebo for patients who have been diagnosed with Type 1 or 2 Diabetes, experiencing painful neuropathy for 6 months to 10 years

IDAHO

Endometriosis
City: Coeur D Alene
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

ILLINOIS

Endometriosis
City: Oak Brook
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

KANSAS

Dysmenorrhea
City: Kansas City
Purpose: To compare pain relief in symptom clusters (abdominal pain, back pain, cramps) between Vipon and ibuprofen.

KENTUCKY

Headache Disorders
City: Lexington
Purpose: A national research study to determine if Patent Foramen Ovale (PFO) closure using the AMPLATZER device can prevent migraine headaches compared to standard medical therapy

Fibromyalgia
City: Lexington
Purpose: Research study that uses a wristwatch-like device to measure sleep in women with fibromyalgia

MASSACHUSETTS

Arthritis/Knee
City: Boston
Purpose: The purpose of this research study is to investigate the safety and tolerability of OP-1 when it is injected into the knee joint of patients who have osteoarthritis on the knee.

Fibromyalgia
City: Springfield
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

Nervous System Diseases
City: Boston
Purpose: research study evaluating investigational drugs to treat pain associated with spinal cord

City: Boston
Purpose: A randomized, double-blind, placebo-controlled, multicenter, crossover study of the safety, efficacy and pharmacokinetics of two escalating, oral doses of V3381 for the treatment of pain from diabetes

NEVADA

Headache Disorders
City: Las Vegas
Purpose: Clinical research study of an investigational oral drug compared to placebo for the treatment of a single moderate or severe headache

NEW JERSEY

Fatigue Syndrome, Chronic
City: New Brunswick
Purpose: In this study 60 people with medically unexplained physical symptoms (MUPS) will receive either a 6-session resilience skill building intervention provided fully online or a weekly computerized journaling assignment. Both programs can be completed from home. Participants will complete questionnaires both before and after the intervention and changes in symptoms, mood and satisfaction with life will be assessed.

Fibromyalgia
City: New Brunswick
Purpose: In this study 60 people with medically unexplained physical symptoms (MUPS) will receive either a 6-session resilience skill building intervention provided fully online or a weekly computerized journaling assignment. Both programs can be completed from home. Participants will complete questionnaires both before and after the intervention and changes in symptoms, mood and satisfaction with life will be assessed.

Irritable Bowel Syndrome
City: New Brunswick
Purpose: In this study 60 people with medically unexplained physical symptoms (MUPS) will receive either a 6-session resilience skill building intervention provided fully online or a weekly computerized journaling assignment. Both programs can be completed from home. Participants will complete questionnaires both before and after the intervention and changes in symptoms, mood and satisfaction with life will be assessed.

NEW YORK

Cancer Pain
City: New York
Purpose: This study will examine the long-term safety of Nasalfent in the treatment of breakthrough cancer pain.

Endometriosis
City: Brooklyn
Purpose: To compare the effectiveness of norethindrone acetate (NA) with GnRH agonist (Lupron-Depot-3) in relieving symptoms of endometriosis, 2) to compare bone density in the two treated groups in order to demonstrate that NA does not affect bone density

Fibromyalgia
City: Rochester
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

Headache Disorders
City: Manlius
Purpose: research study evaluating an investigational drug to see if it helps in the treatment of migraine headaches

NORTH CAROLINA

Arthritis
City: Chapel Hill
Purpose: develop brief versions of the classic 6-week Arthritis Self-Management Program and evaluate their effectiveness.

NORTH DAKOTA

Arthritis/Knee
City: Chapel Hill
Purpose: The purpose of this research study is to investigate the safety and tolerability of OP-1 when it is injected into the knee joint of patients who have osteoarthritis on the knee.

Endometriosis
City: Fargo
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Fibromyalgia
City: Raleigh
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

OHIO

Endometriosis
City: Cleveland
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Fibromyalgia
City: Cleveland
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

OKLAHOMA

Fibromyalgia
City: Oklahoma City
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

OREGON

Fibromyalgia
City: Medford
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

PENNSYLVANIA

Endometriosis
City: Erie
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Fibromyalgia
City: Souderton
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

SOUTH DAKOTA

Endometriosis
City: Watertown
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

TEXAS

Arthritis
City: San Antonio
Purpose: clinical research study of an investigational medication for chronic pain such as osteoarthritis or rheumatoid arthritis

Back Pain
City: San Antonio
Purpose: clinical research study of an investigational medication for chronic pain such as lower back pain

Endometriosis
City: Webster
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Nervous System Diseases
City: Dallas
Purpose: Clinical research study for an investigational medication for diabetic neuropathy in feet, legs, arms or hands?

UTAH

Endometriosis
City: Sandy
Purpose: clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

VERMONT

Fibromyalgia
City: Woodstock
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

VIRGINIA

Fibromyalgia
City: Richmond
Purpose: This trial investigates the efficacy and safety of 4mg/day and 8mg/day of rotigotine as compared to placebo in reducing signs and symptoms of fibromyalgia syndrome.

WASHINGTON

Multiple Sclerosis
City: Kirkland
Purpose: A Study to Test the Use of Duloxetine for Pain in MS


American Academy of Pain Management is the nation's largest interdisciplinary organization serving clinicians who treat people with pain through education, setting standards of care, and advocacy.
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www.aapainmanage.org