New Clinical Trials April 2007
Below are abstracts of recent pain and pain management studies selected from the National Library of Medicine. Click on the link below each entry for the complete abstract.
Arthritis (continued)
Condition: Osteoarthritis of the Knee
State: FL
Purpose: The purpose of this study is to determine if a single or repeat intra-articular injection of Gel-200 is safe and effective in subjects with symptomatic osteoarthritis of the knee and to determine if original SI-6606/01 Gel-200 therapy is durable beyond the original study.
Condition: Osteoarthritis of the Knee
State: FL
Purpose: The purpose of this study is to determine if a single intra-articular injection of Gel-200 is superior to a single injection of PBS in subjects with symptomatic osteoarthritis of the knee.
Condition: Rheumatoid Arthritis
State: MA
Purpose: There are several techniques that medical patients can use to help cope with their illness and their symptoms. In our study, we will compare several of these techniques, and find out which of these can help reduce the pain and discomfort of rheumatoid arthritis for different types of patients.
Back Pain
Condition: Chronic Low Back Pain
State: AL, AZ, CA, CT, FL, IA, KS, LA, MD, MA, NC, OH, OR, PA, TN, TX. UT, WA, WI
Purpose: A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Low Back Pain
Condition: Low Back Pain/Recurrent Lumbar Disc Herniation
State: MO
Purpose: The purpose of this study is to compare patients who underwent decompression/discectomy with pedicle screw fusion to patients who received decompression/discectomy without fusion.
Condition: Low Back Pain
State: NY
Purpose: The objective of this study is to determine if treatment with a flex pad impregnated with static/permanent magnets that can penetrate over 70 mm may improve the quality of chronic lumbar pain with reduction of pain scores.
Condition: Back Pain/Neck Pain
State: NY
Purpose: Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain
Condition: Back Pain
State: SC
Purpose: To study whether duloxetine (Cymbalta ™) 20mg, 60mg, or 120mg once daily compared to placebo (a sugar pill) can help subjects with Chronic Low Back Pain
Condition: Chronic Non-Specific Low Back Pain
State: WA
Purpose: This study will compare the effectiveness of yoga classes, exercise classes, and a self-care book in the management of pain and function for people with low back pain.It will also for physical, psychological and physiological factors associated with improvement in back pain.
Cancer Pain
Condition: Prostate Cancer and Bone Metastases
State: MD
Purpose: This randomized phase II trial is studying samarium Sm 153 lexidronam pentasodium, vaccine therapy, and GM-CSF to see how well they work compared to samarium Sm 153 lexidronam pentasodium alone in treating patients with prostate cancer and bone metastases.
Condition: Prostate Cancer/Pelvic Pain
State: MI
Purpose: The purpose of initiating the urology database is to collect relevant retrospective data via chart review related to patients undergoing radical prostatectomy via the retropubic, perineal, laparoscopic, and robotic assisted laparoscopic approaches and InterStim implantation. This data will be utilized to evaluate the health benefits and outcomes of each of these procedures to enhance care and treatment.
Digestive System Diseases
Condition: Gastrointestinal Ulcers (ibuprofen-associated)
State: PA
Purpose: The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
Fibromyalgia
Condition: Fibromyalgia
State: AZ, FL, GA, IL, IN, MA, MD, NC, OH, TN, TX, VA, WA
Purpose: 15 week clinical research study of an investigational treatment for Fibromyalgia Syndrome
Condition: Fibromyalgia
State: CA, PA, WA
Purpose: To determine the safety and efficacy of Fralex Neuromodulation Therapy (F-NMT), delivered by the Fralex PRIMA device, in reducing chronic musculoskeletal pain associated with Fibromyalgia
Condition: Fibromyalgia
State: CT
Purpose: To evaluate the safety and effectiveness of an investigational drug for the treatment of fibromyalgia
Condition: Fibromyalgia
State: FL
Purpose: A clinical research study of an investigational medication
Condition: Fibromyalgia
State: MA
Purpose: Efficacy and tolerability study of 4 fixed oral doses of DVS SR in adult outpatients with fibromyalgia syndrome
Condition: Fibromyalgia
State: NC
Purpose: Efficacy study of Xyrem® (sodium oxybate) in subjects with fibromyalgia
Condition: Fibromyalgia
State: PA
Purpose: Your blood sample may help researchers gain valuable information and help advance medical research
Headache Disorders
Condition: Migraine Headaches
State: AL
Purpose: Study on an investigational medication for migraine prevention
Condition: Migraine With Aura
State: CA
Purpose: Evaluating Efficacy and Safety of Transcranial TMS Stimulation (TMS) for the Preemptive Treatment of Migraine With Aura
Condition: Migraine
State: NC
Purpose: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Efficacy and Safety Of 100mg/Day and 300mg/Day Lacosamide for Migraine Prophylaxis
Condition: Migraine
State: NC
Purpose: A Study of Combination Product (sumatriptan succinate and naproxen sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Eletriptan
Condition: Migraine/ Tension-Type Headache
State: NY
Purpose: The goal of this study is to compare two medications, naproxen and sumatriptan, to determine which is better for the treatment of recurrent headache within 24 hours of emergency department discharge.
Condition: Migraine
State: OH
Purpose: A clinical research study of an investigational medication for Migraine Headaches
Condition: Migraine
State: PA
Purpose: A research study evaluating the safety and effectiveness of an investigational drug for the treatment of migraines
Condition: Migraine
State: PA
Purpose: A single-center, open-label, pilot trial to collect and evaluate data on the safety and efficacy of duloxetine in the preventive treatment of subjects experiencing episodic migraine headaches
Musculoskeletal Diseases
Condition: Patellofemoral Pain Syndrome
State: KY
Purpose: The purpose of this study is to determine how different exercises affect pain, strength, muscle activity, and function in female subjects with patellofemoral pain.
Condition: Hip Arthroplasty
State: NY
Purpose: Prospective Evaluation of the Clinical and Economic Outcomes of Total Joint Replacement: The HSS Hip Arthroplasty Cohort
Condition: Knee Arthroplasty
State: NY
Purpose: Evaluation of the Clinical and Economic Outcomes of Total Joint Replacement: The HSS Knee Arthroplasty Cohort
Nervous System Diseases
Condition: Painful Diabetic Peripheral Neuropathy
State: AR
Purpose: This study tests the safety and effectiveness of 3 different doses of an investigational drug compared to placebo.
Condition: Pain associated with spinal cord injury
State: MA
Purpose: Study will evaluate investigational drugs to treat pain associated with spinal cord.
Condition: Pain From Diabetes
State: MA
Purpose: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Crossover Study of the Safety, Efficacy and Pharmacokinetics of Two Escalating, Oral Doses of V3381
Condition: Pain from Diabetes
State: MA
Purpose: A research study investigating the use of Pregabalin for Painful Diabetic Neuropathy
Condition: Pain or numbness from Diabetes
State: TX
Purpose: Diabetic Pain Research Study
Pain /therapy (general)
Condition: Chronic Pain
State: IN
Purpose: The purpose of this study is to determine if a stepped-care intervention makes pain symptoms better and reduces activity limitations because of pain. Our two primary hypotheses are that in Operation Iraqi Freedom/Operation Enduring Freedomveterans with chronic pain.
Condition: Chronic Pain
State: MA
Purpose: To examine the effect of opioid analgesics on pain threshold
Condition: Chronic Pain
State: NC
Purpose: A Randomized, Double-Blind, Phase 3 Study of the Efficacy and Safety of HZT-501 in Subjects Requiring NSAID Treatment
Condition: Chronic Pain
State: WA
Purpose: Clinical research study of an investigational medication.
Pelvic Pain
Condition: Endometriosis
State: AL, GA, IL, MD, MI, MO, SC, VA, WI
Purpose: To evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis
Condition: Menstruation, Painful
State: KS
Purpose: To compare pain relief in symptom clusters (abdominal pain, back pain, cramps) between Vipon and ibuprofen
Condition: Chronic Prostatitis / Chronic Pelvic Pain Syndrome
State: MA
Purpose: To evaluate the efficacy and safety of 10mg alfuzosin in the treatment of chronic prostatitis / chronic pelvic pain syndrome
Urologic Diseases
Condition: Interstitial Cystitis/Painful Bladder Syndrome
State: CA, IL, IA, MD, MI, NY, PA, WA
Purpose: To investigate the safety and effectiveness of a medication called CellCept in treating refractory (has not responded to other treatments) interstitial cystitis.
Vascular Diseases
Condition: Critical Limb Ischemia
State: AZ, IL
Purpose: This study will evaluate UT-15C sustained release tablets in subjects experiencing ischemic lower limb rest pain related to advanced peripheral arterial disease.
Vulvar Diseases
Condition: Vulvar Vestibulitis
State: NC
Purpose: is is a study to assess if topical lidocaine will improve symptoms in women with vulvar vestibulitis. It compares use of nightly 5% topical lidocaine ointment to placebo ointment.
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