The Academy is pleased to provide you with access to information about the latest clinical trials in pain management.

~March 2007

New Clinical Trials March 2007
Below are abstracts of recent pain and pain management studies selected from the National Library of Medicine. Click on the link below each entry for the complete abstract.

Endometriosis

Condition: Endometriosis
State: AZ , CA, CO,CT, FL, ID, IL, IN, KS, LA. MA, MT, NC, ND, OH, OR, PA, SC, TX, UT, VT, WA
Purpose: a clinical study to evaluate an investigational oral pill, compared to depo-subQ provera 104TM (DMPA-SC) for the treatment of endometriosis.

Headache Disorders

Condition: Migraine
State: NC
Purpose: Efficacy and Safety Trial of Lacosamide for the Treatment of Migraine Prophylaxis

Condition: Migraine
State: PA
Purpose: A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After

Condition: Migraine
State: ?
Purpose: The purpose of this study is to investigate the efficacy and safety of MK-0974 compared to a placebo for acute migraine.

Musculoskeletal Diseases

Condition: Cervical Facet Arthropathy
State: CA
Purpose: Lidoderm 5% Topical Patch: A phase IV, open label, 3 month prospective randomized controlled, single center study in subjects with pain due to cervical facet arthropathy, "Whiplash

Condition: Lateral Elbow Pain, deQuervain’s Tendonitis, or CMC Arthritis
State: MA
Purpose: The purpose of the study is to compare the effectiveness of a steroid injection to a placebo (inactive substance) in the treatment of lateral elbow pain, deQuervain’s tendonitis, or CMC (thumb) arthritis.

Condition: Osteoarthritis (Glenohumeral)
State: CA, CO, FL. MA, TX, VI, WA
Purpose: A comparison of Orthovisc to corticosteroid injections in the shoulder for pain due to osteoarthritis.

Nervous System Diseases

Condition: Complex Regional Pain Syndrome Type II
State: PA
Purpose: The purpose of this study is to examine the short and long-term benefits of implementing early advanced regional anesthesia techniques for pain control, such as reducing pain disability and the incidence and severity of mental health disorders, following major traumatic injuries to extremities encountered during combat in the Iraqi/Afghanistan war.

Condition: Diabetic Peripheral Neuropathy
State: FL
Purpose: Phase IV, Open-Label Trial evaluating the safety and efficacy of Cesamet for the symptomatic treatment of pain in patients with Diabetic Peripheral Neuropathy. Phase IV, Open-Label Trial evaluating the safety and efficacy of Cesamet for the symptomatic treatment of pain in patients with Diabetic Peripheral Neuropathy

Condition: Neuropathic Pain
State: FL
Purpose: Phase IV, Open-Label Trial evaluating the safety and efficacy of Cesamet for the symptomatic treatment of Chemotherapy-Induced Neuropathic Pain in Patients with Cancer

Condition: Pain Associated with Spinal Cord Injury
State: MA
Purpose: The Department of Anesthesia at Brigham and Women’s Hospital is conducting a research study evaluating investigational drugs to treat pain associated with spinal cord injury (SCI).

Pelvic Pain

Condition: Condition: Interstitial Cystitis, Painful Bladder Syndrome, Chronic Prostatitis, Chronic Pelvic Pain Syndrome
State: CA, IL, MI, OH
Purpose: The purpose of this study is to determine if a randomized trial of physical therapy for pelvic pain is feasible.

Condition: Pelvic Pain
State: NY
Purpose: Nicotine and Pelvic Pain


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